Analysis of a large prospective study of more than 400,000 people found that men who drank four to five cups of coffee daily reduced their risk of death over a 13-year period by 12%, while women’s risk dropped by 16%, according to Neal Freedman, PhD, of the National Cancer Institute, and colleagues.
Compared with non-drinkers, there was little effect for those who drank some coffee, but less than a cup a day. But for more coffee, the odds of death dropped significantly. Specifically:
For those who drank one cup a day, the odds ratios for death were 0.94 for men and 0.95 for women (95% CI 0.90 to 0.99 and 0.90 to 1.01, respectively).
For two or three cups a day, the odds ratios for death were 0.90 for men and 0.87 for women (95% CI 0.86 to 0.93 and 0.83 to 0.92, respectively).
For four or five cups a day, the odds ratios for death were 0.88 for men and 0.84 for women (95% CI 0.84 to 0.93 and 0.79 to 0.90, respectively).
And for six or more cups a day, the odds ratio for death were 0.90 for men and 0.85 for women (95% CI 0.85 to 0.96 and 0.78 to 0.93, respectively).
For both men and women the trend was significant at P<0.001.
Apparently, even decaffeinated coffee appeared to be beneficial – “good news” for people who like coffee but fear caffeine. Just remember to drink it without sugar.